The PDK1/PDPK1 Polyclonal Antibody (CAB10006) is a valuable tool for researchers studying PDK1/PDPK1, a key protein involved in cellular signaling pathways related to cell growth, survival, and metabolism. This antibody is raised in rabbits and has high reactivity with human samples, making it a reliable choice for Western blot applications.PDK1/PDPK1 is a crucial enzyme that plays a pivotal role in the PI3K/Akt signaling pathway, which is often dysregulated in various diseases, including cancer, diabetes, and cardiovascular disorders. By targeting PDK1/PDPK1, researchers can gain insights into the mechanisms underlying these diseases and potentially develop new therapeutic strategies.
With its ability to specifically bind to PDK1/PDPK1 protein, this polyclonal antibody enables accurate detection and analysis in a variety of cell types, making it a versatile tool for studies in cell biology, oncology, and drug development. By studying the functions of PDK1/PDPK1, researchers can uncover novel insights into disease mechanisms and identify potential targets for innovative treatments.
Product Name:
PDK1/PDPK1 Polyclonal Antibody
SKU:
CAB21810
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 409-556 of human PDK1/PDPK1 (NP_002604.1).
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
5170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDK1/PDPK1 antibody (CAB21810) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
