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PDK1/PDHK1 Monoclonal Antibody (CAB24749)

SKU:
CAB24749
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$635
Frequently bought together:

Description

PDK1/PDHK1 Monoclonal Antibody (CAB24749)

The PDK1/PDHK1 Monoclonal Antibody (CAB24749) is a valuable tool for researchers studying the PDK1 and PDHK1 proteins, which play essential roles in regulating cellular metabolism and energy production. This monoclonal antibody, produced through hybridoma technology, specifically targets PDK1 and PDHK1 in human samples, providing accurate and reliable results in experiments such as Western blotting.PDK1 and PDHK1 are key enzymes involved in the regulation of glucose metabolism and the production of ATP in cells. Dysregulation of these proteins has been linked to various diseases, including cancer and metabolic disorders.

By using the PDK1/PDHK1 Monoclonal Antibody, researchers can gain insights into the expression levels and localization of these proteins in different cell types, aiding in the study of metabolic pathways and potential therapeutic targets.Overall, the PDK1/PDHK1 Monoclonal Antibody (CAB24749) is a valuable tool for researchers interested in understanding the intricate mechanisms of cellular metabolism and energy regulation, with potential implications for the development of novel therapeutic strategies for metabolic disorders and cancer.

Product Name:PDK1/PDHK1 Monoclonal Antibody
Product Code:CAB24749
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC1355
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Mitochondrion matrix

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDK1/PDHK1 (Q15118).
Sequence:Email for sequence
Synonyms:PDK1, pyruvate dehydrogenase kinase 1
Calculated MW:49kDa
Observed MW:49kDa

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