The PDILT Polyclonal Antibody (PACO60220) is a valuable tool for researchers studying protein disulfide isomerase-like protein of the testis (PDILT). PDILT is involved in the regulation of disulfide bond formation and protein folding in the testis, playing a crucial role in sperm maturation and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to PDILT, this antibody enables the detection and analysis of PDILT expression levels in various cell types, making it an ideal choice for studies in reproductive biology and fertility research.
PDILT dysfunction has been linked to male infertility and other reproductive disorders, making it a promising target for therapeutic interventions. Understanding the role of PDILT in sperm function and reproductive health is essential for developing new strategies to address infertility issues and improve reproductive outcomes. The PDILT Polyclonal Antibody is a valuable tool for researchers aiming to unravel the complex mechanisms underlying male fertility and reproductive function.
Antibody Name:
PDILT Antibody (PACO60220)
Antibody SKU:
PACO60220
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein disulfide-isomerase-like protein of the testis protein (494-584AA)
Western Blot. Positive WB detected in: A549 whole cell lysate, Colo320 whole cell lysate. All lanes: PDILT antibody at 4.63µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 67 kDa. Observed band size: 67 kDa.
Background:
Probable redox-inactive chaperone involved in spermatogenesis.
Synonyms:
Protein disulfide-isomerase-like protein of the testis, PDILT
UniProt Protein Function:
PDILT: Probable redox-inactive chaperone involved in spermatogenesis. Belongs to the protein disulfide isomerase family.Chromosomal Location of Human Ortholog: 16p12.3Cellular Component: endoplasmic reticulumMolecular Function: protein disulfide isomerase activityBiological Process: protein folding
