PDIA2 Rabbit Polyclonal Antibody (CAB12789)
- SKU:
- CAB12789
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDIA2 Rabbit Polyclonal Antibody |
SKU: | CAB12789 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 326-525 of human PDIA2 (NP_006840.2). |
Sequence: | FGLK AEAA PTLR LVNL ETTK KYAP VDGG PVTA ASIT AFCH AVLN GQVK PYLL SQEI PPDW DQRP VKTL VGKN FEQV AFDE TKNV FVKF YAPW CTHC KEMA PAWE ALAE KYQD HEDI IIAE LDAT ANEL DAFA VHGF PTLK YFPA GPGR KVIE YKST RDLE TFSK FLDN GGVL PTEE PPEE PAAP FPEP PANS TMGS KEEL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PDI; PDA2; PDIP; PDIR; PDIA2 |
Positive Sample: | U-87MG,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum lumen. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.
Purification Method: | Affinity purification |
Gene ID: | 64714 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |