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PDHX Monoclonal Antibody [PAT1E11AT] (CPAB0269)

SKU:
CPAB0269
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1 
Clone:
PAT1E11AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

PDHX Monoclonal Antibody [PAT1E11AT] (CPAB0269)

The PDHX Monoclonal Antibody (CPAB0269) is a valuable tool for researchers studying PDHX, a key enzyme involved in the pyruvate dehydrogenase complex. This antibody, produced in mice, exhibits high specificity and sensitivity towards human samples and is validated for use in various applications, including Western blot and immunohistochemistry.PDHX, also known as pyruvate dehydrogenase complex component X, plays a crucial role in the conversion of pyruvate to acetyl-CoA, a key step in cellular metabolism. Dysregulation of PDHX activity has been linked to diseases such as metabolic disorders and various cancers, highlighting its importance in health and disease.

By targeting PDHX with this specific monoclonal antibody, researchers can study its expression and function in different cell types and tissue samples, providing valuable insights into metabolic processes and potential therapeutic strategies for related conditions. This antibody is a valuable tool for furthering our understanding of PDHX biology and its implications for human health.

Product Name:PDHX Antibody
Product Sku:CPAB0269
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PDHX mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDHX amino acids 54-51 purified from Ecoli.
Clone:PAT1E11AT
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PDHX antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1 
Background:Pyruvate Dehydrogenase Complex, Component X, also known as PDHX, encodes the E3 binding protein subunit of the PDH complex which contains 3 catalytic subunits. PDHX tethers E3 dimers to the E2 core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is critical for a functional PDH complex.
Synonyms:DLDBP, E3BP, OPDX, PDX1, proX, Component X.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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