PDHB Rabbit Polyclonal Antibody (CAB6943)
- SKU:
- CAB6943
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PDHB Rabbit Polyclonal Antibody |
SKU: | CAB6943 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PDHB (NP_000916.2). |
Sequence: | MAAV SGLV RRPL REVS GLLK RRFH WTAP AALQ VTVR DAIN QGMD EELE RDEK VFLL GEEV AQYD GAYK VSRG LWKK YGDK RIID TPIS EMGF AGIA VGAA MAGL RPIC EFMT FNFS MQAI DQVI NSAA KTYY MSGG LQPV PIVF RGPN GASA GVAA QHSQ CFAA WYGH CPGL KVVS PWNS EDAK GLIK SAIR DNNP VVVL ENEL MYGV PFEF PPEA QSKD FLIP IGKA KIER QGTH ITVV SHSR PVGH CLEA AAVL SKEG VECE VINM RTIR PMDM ETIE ASVM KTNH LVTV EGGW PQFG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PDHBD; PHE1B; E1beta; PDHE1B; PDHE1-B; PDHB |
Positive Sample: | HL-60,HeLa,Jurkat,U-937,Mouse skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5162 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |