The PDHA2 Polyclonal Antibody (CAB16944) is a powerful tool for researchers studying the pyruvate dehydrogenase E1 component subunit alpha (PDHA2) protein. This antibody, raised in rabbits, exhibits high specificity and sensitivity in detecting PDHA2 in human samples, making it a valuable asset in Western blot applications.PDHA2 is an essential enzyme involved in the conversion of pyruvate to acetyl-CoA, a key step in aerobic respiration. Dysregulation of PDHA2 has been implicated in various metabolic disorders, making it a target of interest in research on conditions such as diabetes and cancer.
The PDHA2 Polyclonal Antibody enables precise detection and analysis of PDHA2 levels in different cell types, offering insights into its role in cellular metabolism and disease progression.By using the PDHA2 Polyclonal Antibody, researchers can deepen their understanding of PDHA2 function and explore its potential as a therapeutic target in metabolic diseases. This antibody's reliability and specificity make it a valuable tool in advancing research in the fields of biochemistry, metabolism, and cell biology.
Product Name:
PDHA2 Rabbit Polyclonal Antibody
SKU:
CAB16944
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of mouse PDHA2 (NP_032837.1).
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Is expressed in nervous system and testis. Orthologous to human PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2).
Purification Method:
Affinity purification
Gene ID:
18598
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDHA2 Rabbit pAb (CAB16944) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
