The PDHA2 Polyclonal Antibody (CAB9943) is specifically designed for research involving the pyruvate dehydrogenase E1 component subunit alpha (PDHA2) protein. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the PDHA2 protein, this antibody enables the detection and analysis of PDHA2 in various cell types, making it ideal for research in biochemistry, metabolism, and mitochondrial function.PDHA2 is a crucial component of the pyruvate dehydrogenase complex, which plays a key role in the conversion of pyruvate into acetyl-CoA in the mitochondria.
Dysregulation of PDHA2 has been implicated in various metabolic disorders, including pyruvate dehydrogenase deficiency and some types of cancer. Understanding the function and regulation of PDHA2 is essential for unraveling the complex mechanisms of metabolism and identifying potential therapeutic targets for metabolic diseases.Overall, the PDHA2 Polyclonal Antibody (CAB9943) is a valuable tool for researchers studying PDHA2 and its role in metabolic pathways, offering insights that could lead to new advancements in the treatment of metabolic disorders and cancer.
Product Name:
PDHA2 Rabbit Polyclonal Antibody
SKU:
CAB9943
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 119-388 of human PDHA2 (NP_005381.1).
Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in pyruvate metabolic process. Located in mitochondrion and nucleolus.
Purification Method:
Affinity purification
Gene ID:
5161
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDHA2 antibody (CAB9943) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
