The PDHA2 Polyclonal Antibody (CAB14994) is a valuable tool for researchers studying the pyruvate dehydrogenase E1 component subunit alpha 2 (PDHA2) protein. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.PDHA2 is an essential component of the pyruvate dehydrogenase complex, which plays a crucial role in the conversion of pyruvate to acetyl-CoA in the mitochondria. Dysregulation of this complex has been linked to various metabolic disorders and diseases, making PDHA2 a key target for research in the fields of metabolism and biochemistry.
By using the PDHA2 Polyclonal Antibody, researchers can effectively detect and analyze the PDHA2 protein in a variety of cell types, providing valuable insights into its function and potential implications in disease. This antibody is a valuable tool for studies investigating metabolic disorders, mitochondrial function, and related pathways, offering new opportunities for advancements in these research areas.
Product Name:
PDHA2 Rabbit Polyclonal Antibody
SKU:
CAB14994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-391 of mouse PDHA2 (NP_032837.1).
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Is expressed in nervous system and testis. Orthologous to human PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2).
Purification Method:
Affinity purification
Gene ID:
18598
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDHA2 Rabbit pAb (CAB14994) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
