PDGFRA Rabbit Polyclonal Antibody (CAB2103)
- SKU:
- CAB2103
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDGFRA Rabbit Polyclonal Antibody |
SKU: | CAB2103 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 896-1059 of human PDGFR alpha (NP_006197.1). |
Sequence: | YPGM MVDS TFYN KIKS GYRM AKPD HATS EVYE IMVK CWNS EPEK RPSF YHLS EIVE NLLP GQYK KSYE KIHL DFLK SDHP AVAR MRVD SDNA YIGV TYKN EEDK LKDW EGGL DEQR LSAD SGYI IPLP DIDP VPEE EDLG KRNR HSSQ TSEE SAIE TGSS SSTF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CD140A; PDGFR2; PDGFR-2; PDGFR alpha |
Positive Sample: | C6,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 123kDa |
Observed MW: | 150-190kDa |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Purification Method: | Affinity purification |
Gene ID: | 5156 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |