Based on the information from the URL provided, the PDGFD Polyclonal Antibody (CAB8263) is a valuable tool for researchers studying PDGFD, a protein involved in cell growth and development, specifically in the context of cancer biology and tumor progression. This antibody, produced using rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.PDGFD, a member of the platelet-derived growth factor family, is known to play a crucial role in promoting cell proliferation, migration, and survival, making it a key player in various cellular processes, including angiogenesis and tissue remodeling.
By targeting PDGFD, researchers can gain insights into its function and potential therapeutic implications in cancer and other diseases where aberrant growth factor signaling is implicated.The PDGFD Polyclonal Antibody enables the specific detection and analysis of PDGFD protein expression in different cell types, offering researchers a valuable tool for investigating the role of PDGFD in various physiological and pathological conditions. Its high specificity and sensitivity make it suitable for a wide range of applications in cancer research and other areas of biomedical research focused on growth factor signaling pathways.
Product Name:
PDGFD Rabbit Polyclonal Antibody
SKU:
CAB8263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PDGFD (NP_079484.1).
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
80310
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDGFD antibody (CAB8263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
