The PDGFD Polyclonal Antibody (CAB14653) is a specialized research tool designed for the study of PDGFD, a critical growth factor involved in various physiological processes. This antibody, produced in rabbits, exhibits high specificity and robust reactivity with human samples, making it an ideal choice for Western blot applications.PDGFD is a key player in the regulation of cell proliferation, migration, and survival, making it an attractive target for investigations in developmental biology, angiogenesis, and tissue repair. The PDGFD Polyclonal Antibody binds specifically to the PDGFD protein, allowing for precise detection and analysis in a variety of cell types and experimental settings.
By understanding the intricate functions of PDGFD, researchers can gain valuable insights into its role in various pathologies, including cancer, cardiovascular diseases, and fibrosis. This antibody serves as a valuable tool for advancing our knowledge of PDGFD biology and potentially identifying new therapeutic strategies targeting this important growth factor.
Product Name:
PDGFD Rabbit Polyclonal Antibody
SKU:
CAB14653
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PDGFD (NP_079484.1).
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
80310
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDGFD antibody (CAB14653) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
