The PDGFC Polyclonal Antibody (CAB15174) is a vital tool for researchers studying PDGFC, a growth factor involved in various cellular processes, particularly in cell growth and development. This antibody, produced in rabbits, exhibits strong reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the PDGFC protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential tool for investigations in cell biology and cancer research.PDGFC, also known as platelet-derived growth factor C, plays a crucial role in cellular communication and tissue repair, making it a key player in processes such as wound healing and angiogenesis.
Its involvement in promoting cell proliferation and migration underscores its significance in various physiological and pathological conditions, making it a promising target for therapeutic interventions in diseases like cancer and cardiovascular disorders. The PDGFC Polyclonal Antibody offers researchers the opportunity to deepen their understanding of PDGFC's functions and potential applications in biomedical research.
Product Name:
PDGFC Rabbit Polyclonal Antibody
SKU:
CAB15174
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 166-345 of human PDGFC (NP_057289.1).
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
56034
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDGFC Rabbit pAb (CAB15174) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
