PDGFB Rabbit Polyclonal Antibody (CAB1195)
- SKU:
- CAB1195
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PDGFB Rabbit Polyclonal Antibody |
SKU: | CAB1195 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 140-241 of human PDGFB (NP_002599.1). |
Sequence: | QCRP TQVQ LRPV QVRK IEIV RKKP IFKK ATVT LEDH LACK CETV AAAR PVTR SPGG SQEQ RAKT PQTR VTIR TVRV RRPP KGKH RKFK HTHD KTAL KETL GA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2; PDGFB |
Positive Sample: | A-549,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5155 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |