PDGFB Monoclonal Antibody (CAB22036)
- SKU:
- CAB22036
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
Product Name: | PDGFB Monoclonal Antibody |
SKU: | CAB22036 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 142-241 of human PDGFB (NP_002599.1). |
Sequence: | RPTQ VQLR PVQV RKIE IVRK KPIF KKAT VTLE DHLA CKCE TVAA ARPV TRSP GGSQ EQRA KTPQ TRVT IRTV RVRR PPKG KHRK FKHT HDKT ALKE TLGA |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2; PDGFB |
Positive Sample: | NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 27kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5155 |
Clone Number: | ARC53713 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |