PDE8A Rabbit Polyclonal Antibody (CAB12187)
- SKU:
- CAB12187
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | PDE8A Rabbit Polyclonal Antibody |
SKU: | CAB12187 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1). |
Sequence: | MGCA PSIH ISER LVAE DAPS PAAP PLSS GGPR LPQG QKTA ALPR TRGA GLLE SELR DGSG KKVA VADV QFGP MRFH QDQL QVLL VFTK EDNQ CNGF CRAC EKAG FKCT VTKE AQAV LACF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HsT19550; PDE8A |
Positive Sample: | Mouse testis,Mouse eye,Mouse liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome |
Calculated MW: | 93kDa |
Observed MW: | 93kDa |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5151 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |