The PDE7A Polyclonal Antibody (CAB15079) is a powerful tool for researchers studying phosphodiesterase 7A, an enzyme involved in the regulation of cyclic nucleotide signaling pathways. This antibody, produced in rabbits, specifically targets the PDE7A protein and is highly reactive with human samples. Validated for use in Western blot applications, the PDE7A Polyclonal Antibody allows for the detection and analysis of PDE7A in various cell types.PDE7A is known to play a role in a variety of physiological processes, including immune response, inflammation, and neuronal signaling. Dysregulation of PDE7A has been linked to various diseases, making it an attractive target for drug discovery and therapeutic intervention.
By studying the activity of PDE7A, researchers can gain valuable insights into its potential as a target for the treatment of conditions such as autoimmune disorders, neurodegenerative diseases, and cancer.Overall, the PDE7A Polyclonal Antibody is a valuable tool for researchers investigating the function of PDE7A and its potential implications in human health and disease. Its high specificity and reactivity make it an essential component of studies in the fields of molecular biology, pharmacology, and drug development.
Product Name:
PDE7A Rabbit Polyclonal Antibody
SKU:
CAB15079
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1).
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
5150
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDE7A Rabbit pAb (CAB15079) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
