PDE6D Rabbit Polyclonal Antibody (CAB14762)
- SKU:
- CAB14762
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | PDE6D Rabbit Polyclonal Antibody |
SKU: | CAB14762 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE6D (NP_002592.1). |
Sequence: | MSAK DERA REIL RGFK LNWM NLRD AETG KILW QGTE DLSV PGVE HEAR VPKK ILKC KAVS RELN FSST EQME KFRL EQKV YFKG QCLE EWFF EFGF VIPN STNT WQSL IEAA PESQ MMPA SVLT GNVI IETK FFDD DLLV STSR VRLF YV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | PDED; JBTS22; PDE6D |
Positive Sample: | HT-29,OVCAR3,Mouse brain,Mouse kidney,Mouse lung,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle membrane, Peripheral membrane protein, cilium basal body, cytoskeleton, cytosol. |
Calculated MW: | 17kDa |
Observed MW: | 14-15kDa |
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Purification Method: | Affinity purification |
Gene ID: | 5147 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |