PDE5A Rabbit Polyclonal Antibody (CAB6831)
- SKU:
- CAB6831
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDE5A Rabbit Polyclonal Antibody |
SKU: | CAB6831 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE5A (NP_001074.2). |
Sequence: | MERA GPSF GQQR QQQQ PQQQ KQQQ RDQD SVEA WLDD HWDF TFSY FVRK ATRE MVNA WFAE RVHT IPVC KEGI RGHT ESCS CPLQ QSPR ADNS APGT PTRK ISAS EFDR PLRP IVVK DSEG TVSF LSDS EKKE QMPL TPPR FDHD EGDQ CS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CN5A; PDE5; CGB-PDE; PDE5A |
Positive Sample: | HT-1080,SKOV3,A-549,22Rv1,Mouse brain,Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 100kDa |
Observed MW: | 100kDa |
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 8654 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |