The PDE4C Polyclonal Antibody (CAB13038) is a valuable tool for researching PDE4C, one of the isoforms of the phosphodiesterase 4 (PDE4) enzyme family. PDE4 enzymes play a crucial role in regulating intracellular levels of cyclic AMP (cAMP), a key signaling molecule in various cellular processes. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to the PDE4C protein, researchers can detect and analyze its expression in different cell types, providing insights into its function in cellular signaling pathways.As a member of the PDE4 enzyme family, PDE4C has been implicated in a range of physiological and pathological processes, including inflammation, immune response, and neurological disorders.
Understanding the role of PDE4C in these processes is essential for developing targeted therapies for conditions such as inflammatory diseases, asthma, and psychiatric disorders.Overall, the PDE4C Polyclonal Antibody (CAB13038) offers researchers a reliable tool for investigating the function and regulation of PDE4C in various biological contexts, contributing to advances in drug discovery and therapeutic interventions.
Product Name:
PDE4C Polyclonal Antibody
SKU:
CAB13038
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 638-712 of human PDE4C (NP_000914.2).
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
5143
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of PC-12 cells using PDE4C Rabbit pAb (CAB13038) at dilution of 1:400 (40x lens).Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
