PDE4B Polyclonal Antibody (CAB23257)
- SKU:
- CAB23257
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | PDE4B Polyclonal Antibody |
SKU: | CAB23257 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 636-736 of human PDE4B (NP_002591.2). |
Sequence: | PDAQ DILD TLED NRNW YQSM IPQS PSPP LDEQ NRDC QGLM EKFQ FELT LDEE DSEG PEKE GEGH SYFS STKT LCVI DPEN RDSL GETD IDIA TEDK SPVD T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DPDE4; PDEIVB; PDE4B |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytosol, dendritic spine, excitatory synapse, gamma-tubulin complex, nucleus, perinuclear region of cytoplasm, postsynaptic density, synaptic vesicle, Z disc |
Calculated MW: | 83kDa |
Observed MW: | 90kDa |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5142 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |