PDE1C Rabbit Polyclonal Antibody (CAB15078)
- SKU:
- CAB15078
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDE1C Rabbit Polyclonal Antibody |
SKU: | CAB15078 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 435-634 of human PDE1C (NP_001177985.1). |
Sequence: | VEPT FTVL TDMT EKIV SPLI DETS QTGG TGQR RSSL NSIS SSDA KRSG VKTS GSEG SAPI NNSV ISVD YKSF KATW TEVV HINR ERWR AKVP KEEK AKKE AEEK ARLA AEEQ QKEM EAKS QAEE GASG KAEK KTSG ETKN QVNG TRAN KSDN PRGK NSKA EKSS GEQQ QNGD FKDG KNKT DKKD HSNI GNDS KKTD DSQE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Hcam3; DFNA74; hCam-3; cam-PDE 1C; PDE1C |
Positive Sample: | HepG2,mouse heart,mouse brain,mouse testis,rat heart,rat brain,rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, lysosome |
Calculated MW: | 81kDa |
Observed MW: | 81kDa |
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Purification Method: | Affinity purification |
Gene ID: | 5137 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |