The PDCD4 Polyclonal Antibody is a valuable tool for research involving Programmed Cell Death 4 (PDCD4), a tumor suppressor protein that plays a role in regulating cell growth and apoptosis. This antibody, generated in rabbits, is highly specific to PDCD4 and is validated for use in various applications, including Western blotting and immunohistochemistry.PDCD4 is known to be dysregulated in various cancer types, making it a promising target for cancer research and drug development. By detecting and analyzing PDCD4 expression in cells and tissues, researchers can gain insight into the underlying mechanisms of tumorigenesis and potentially identify novel therapeutic strategies.
Furthermore, PDCD4 has been implicated in other biological processes, such as inflammation and immune response regulation. Studying the function of PDCD4 in these contexts can provide valuable information for understanding diseases like autoimmune disorders and chronic inflammatory conditions.Overall, the PDCD4 Polyclonal Antibody offers researchers a reliable tool for investigating the role of PDCD4 in cancer biology, immunology, and beyond. Its high specificity and sensitivity make it ideal for a wide range of research applications, ultimately contributing to advancements in our understanding of disease mechanisms and potential therapeutic interventions.
Product Name:
PDCD4 Polyclonal Antibody
SKU:
CAB21435
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-260 of human PDCD4 (NP_055271.2).
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Hep G2 cells using PDCD4 Rabbit pAb(CAB21435) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
