The PDCD4 Polyclonal Antibody (CAB2420) is a valuable tool for research involving the programmed cell death 4 (PDCD4) protein, which is known for its role in regulating cell apoptosis and tumor suppression. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PDCD4 protein, researchers can easily detect and analyze its expression in various cell types, making it a valuable asset for studies in cancer research and cell biology.PDCD4 is a tumor suppressor protein that is involved in various cellular processes, including cell proliferation, differentiation, and migration.
Dysregulation of PDCD4 has been implicated in the development and progression of cancer, making it a promising target for therapeutic interventions. By studying the function and regulation of PDCD4, researchers can gain insights into potential treatment strategies for cancer and other diseases related to abnormal cell growth.Overall, the PDCD4 Polyclonal Antibody (CAB2420) offers researchers a reliable tool for investigating the role of PDCD4 in cancer biology and beyond. Its specificity and sensitivity make it an essential component for studies aiming to elucidate the molecular mechanisms underlying tumorigenesis and potential therapeutic targets in cancer treatment.
Product Name:
PDCD4 Rabbit Polyclonal Antibody
SKU:
CAB2420
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_055271.2).
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDCD4 Rabbit pAb (CAB2420).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
