The PDCD2 Polyclonal Antibody (CAB15299) is a valuable tool for researchers studying PDCD2, a protein involved in apoptotic cell death and DNA repair processes. This antibody, generated in rabbits, exhibits high specificity for PDCD2 in human samples and is suitable for Western blot applications. By binding to the PDCD2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.PDCD2, also known as programmed cell death protein 2, plays a crucial role in regulating cell survival and apoptosis, making it a key player in maintaining cellular homeostasis.
Its involvement in DNA repair mechanisms also highlights its potential significance in cancer development and progression. By understanding the function of PDCD2, researchers can gain insights into the underlying mechanisms of diseases like cancer and potentially identify new therapeutic targets for treatment.
Product Name:
PDCD2 Rabbit Polyclonal Antibody
SKU:
CAB15299
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human PDCD2 (NP_002589.2).
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
Purification Method:
Affinity purification
Gene ID:
5134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDCD2 Rabbit pAb (CAB15299) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
