The PDCD1LG2 Polyclonal Antibody (CAB17943) is a valuable tool for researchers studying PDCD1LG2, a protein involved in immune regulation and the modulation of T cell responses. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the PDCD1LG2 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.PDCD1LG2, also known as Programmed cell death 1 ligand 2, plays a crucial role in regulating immune responses and maintaining immune tolerance.
Its involvement in T cell activation and inhibition makes it a key player in immune checkpoint pathways, making it a promising target for therapeutic research in cancer and autoimmune diseases. Understanding the function of PDCD1LG2 is essential for developing targeted therapies that manipulate immune responses for the treatment of these conditions.
Product Name:
PDCD1LG2 Rabbit Polyclonal Antibody
SKU:
CAB17943
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human PDCD1LG2 (NP_079515.2).
external side of plasma membrane, extracellular region, plasma membrane
Calculated MW:
31kDa
Observed MW:
45-60kDa
Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis.
Purification Method:
Affinity purification
Gene ID:
80380
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDCD1LG2 antibody (CAB17943) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
