PDCD12 Monoclonal Antibody [P3G4AT] (CPAB0571)
- SKU:
- CPAB0571
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- P3G4AT
- Applications:
- WB
- ELISA
- IHC
Description
PDCD12 Monoclonal Antibody [P3G4AT] (CPAB0571)
The PDCD12 Polyclonal Antibody (CPAB0571) is a valuable tool for researchers studying PDCD12, a protein involved in programmed cell death and apoptosis. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the PDCD12 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cell death mechanisms.PDCD12, also known as programmed cell death protein 12, plays a crucial role in the regulation of apoptosis and cell survival pathways.
Its involvement in programmed cell death processes makes it a key target for research into cancer, neurodegenerative diseases, and other conditions characterized by dysregulated cell death. Investigating the function of PDCD12 can provide valuable insights into the mechanisms underlying these diseases and may lead to the development of novel therapeutic strategies targeting cell death pathways.
| Product Name: | PDCD12 Antibody |
| Product Sku: | CPAB0571 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PDCD12 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD12 amino acids 254-362 purified from Ecoli. |
| Clone: | P3G4AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA, Immunohistochemistry |
| Purification Method: | PDCD12 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | PDCD12 (AVEN) represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein which blocks apoptosis impeded by Apaf-1 mediated caspase activation. BAD and Bcl-2 also interact with PDCD12 to prevent apoptosis. PDCD12 is expressed in a wide variety of normal tissues including the heart, skeletal muscle, kidney, liver, testis, and also in diseases such as cancer. |
| Synonyms: | Cell death regulator Aven, AVEN, PDCD12, Programmed Cell Death 12. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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