The PDCD10 Polyclonal Antibody (CAB17094) is a valuable tool for researchers studying PDCD10, also known as Programmed Cell Death 10, a protein involved in apoptosis and cell growth regulation. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in Western blotting applications.PDCD10 is a crucial player in cell signaling pathways that control programmed cell death and cell proliferation. Dysregulation of PDCD10 has been implicated in various diseases, including cancer and neurological disorders. By targeting PDCD10 with this antibody, researchers can gain insights into the protein's function and potential therapeutic implications.
The versatility of the PDCD10 Polyclonal Antibody allows for its use in a wide range of research applications, particularly in the fields of oncology and neurology. Whether investigating the role of PDCD10 in tumorigenesis or neuronal development, this antibody provides reliable and accurate detection of the protein in various biological samples. Unlock the potential of your research with the PDCD10 Polyclonal Antibody.
Product Name:
PDCD10 Rabbit Polyclonal Antibody
SKU:
CAB17094
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
11235
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PDCD10 Rabbit pAb (CAB17094) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
