PDCD1 Monoclonal Antibody [P4F12AT] (CPAB0553)
- SKU:
- CPAB0553
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- P4F12AT
- Applications:
- WB
- ELISA
Frequently bought together:
Description
system_update_alt Datasheet
Product Name: | PDCD1 Antibody |
Product Sku: | CPAB0553 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PDCD1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD1 amino acids 21-167 purified from Ecoli. |
Clone: | P4F12AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | PDCD1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | PDCD1 is a cell surface membrane protein of the immunoglobulin superfamily. PDCD1 is expressed in pro-B-cells and is thought to have a role in their differentiation. In mice, expression of PDCD1 gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for the PDCD1 gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that the PDCD1 gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Synonyms: | Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1, SLEB2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |