The PDAP1 Polyclonal Antibody is a versatile tool for researchers studying the PDAP1 protein, which plays a critical role in protein metabolism and mitochondrial function. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It binds to the PDAP1 protein, allowing for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and biochemistry.PDAP1 is essential for the assembly of the mitochondrial ribosome and the translation of mitochondrial genes, making it a key player in cellular energy production and metabolism.
Dysregulation of PDAP1 has been linked to mitochondrial dysfunction and various metabolic disorders, making it a promising target for research into metabolic diseases and mitochondrial disorders. By understanding the role of PDAP1 in cellular processes, researchers may uncover new insights into disease mechanisms and potential therapeutic strategies.
Product Name:
PDAP1 Polyclonal Antibody
SKU:
CAB4505
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDAP1 (NP_055706.1).
The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity.
Purification Method:
Affinity purification
Gene ID:
11333
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDAP1 Rabbit pAb (CAB4505) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.