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PD-1/CD279 Polyclonal Antibody (CAB23886)

SKU:
CAB23886
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

PD-1/CD279 Polyclonal Antibody (CAB23886)

The PD-1 (CD279) Polyclonal Antibody (CAB23886) is a valuable tool for researchers studying the programmed cell death protein 1 (PD-1), a cell surface receptor crucial for regulating immune responses. This antibody, produced in rabbits, is highly specific for human samples and is ideal for use in Western blot experiments. By targeting the PD-1 protein, researchers can accurately measure and analyze its expression in various cell types, providing insights into its role in immunology and cancer research.

PD-1, also known as programmed death-1 receptor, is a key player in immune checkpoint regulation, controlling T cell activation and preventing autoimmune responses. Dysregulation of PD-1 has been implicated in diseases like cancer, chronic infections, and autoimmune disorders, making it an attractive target for therapeutic interventions. By studying PD-1 with this antibody, researchers can uncover new insights into its function and potential therapeutic applications in immunotherapy.

Product Name:PD-1/CD279 Polyclonal Antibody
Product Code:CAB23886
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:EL4, Mouse thymus, Mouse spleen

Involved in negative regulation of immune response. Acts upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1).

Immunogen:Recombinant protein of mouse PD-1/CD279.
Sequence:Email for sequence
Synonyms:PD-1, Pdc1, Ly101
Calculated MW:32kDa
Observed MW:61kDa

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