The PCYT1B Polyclonal Antibody (PAC01121) is a valuable tool for researchers studying the PCYT1B protein, a key enzyme involved in phosphatidylcholine biosynthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to PCYT1B, this antibody enables the detection and analysis of the enzyme in various cell types, making it an essential tool for studies in lipid metabolism and cancer research.PCYT1B plays a crucial role in the synthesis of phosphatidylcholine, a major component of cell membranes, and dysregulation of this process has been implicated in various diseases, including cancer.
By understanding the function and regulation of PCYT1B, researchers can gain insights into lipid metabolism and potentially uncover new therapeutic targets for cancer treatment. The PCYT1B Polyclonal Antibody is a reliable tool for investigating the roles of this important enzyme in health and disease.
PCYT1B: Controls phosphatidylcholine synthesis. Belongs to the cytidylyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.7.7.15; Lipid Metabolism - glycerophospholipid; TransferaseChromosomal Location of Human Ortholog: Xp22.11Cellular Component: cytoplasm; endoplasmic reticulum membraneMolecular Function: choline-phosphate cytidylyltransferase activityBiological Process: CDP-choline pathway; ovarian follicle development; phosphatidylcholine biosynthetic process; spermatogenesis
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
