The PCPE-1 Monoclonal Antibody is a cutting-edge tool for researchers studying PCPE-1, a protein involved in the regulation of collagen biosynthesis. This monoclonal antibody, generated using hybridoma technology, offers high specificity and sensitivity in detecting PCPE-1 in various biological samples.PCPE-1, also known as procollagen C-endopeptidase enhancer 1, plays a crucial role in the processing of procollagen, a key step in collagen production. Dysregulation of PCPE-1 has been linked to various collagen-related disorders, making it an important target for research in the fields of connective tissue disorders and fibrosis.
This monoclonal antibody is validated for use in techniques such as immunohistochemistry and Western blotting, providing researchers with a reliable tool for investigating the role of PCPE-1 in normal physiological processes and disease pathology. Its high specificity and sensitivity make it an ideal choice for studies aiming to unravel the complex mechanisms underlying collagen metabolism and homeostasis.
Product Name:
PCPE-1 Monoclonal Antibody
SKU:
CAB24732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 304-449 of human TLR4 (NP_002584.2).
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.
Purification Method:
Affinity purification
Gene ID:
5118
Clone Number:
ARC63882
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PCPE-1 Rabbit mAb (CAB24732) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC):THP-1Exposure time: 30s.
