The PCOLCE Polyclonal Antibody (CAB15298) is a valuable tool for researchers studying the PCOLCE protein, which plays a crucial role in the regulation of blood clot formation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the PCOLCE protein, researchers can confidently detect and analyze its expression in various cell types.PCOLCE, also known as platelet collagen receptor, is essential for maintaining hemostasis and preventing excessive bleeding. It acts as a collagen-binding protein, facilitating platelet adhesion and aggregation at sites of vascular injury.
Understanding the function of PCOLCE is vital for uncovering its role in thrombotic disorders and developing targeted therapies for conditions like stroke and heart attack.Overall, the PCOLCE Polyclonal Antibody is a valuable tool for researchers interested in unraveling the complex mechanisms underlying blood clot formation and the pathogenesis of cardiovascular diseases. Its specificity and reliability make it an excellent choice for studies in hematology, vascular biology, and cardiovascular research.
Product Name:
PCOLCE Rabbit Polyclonal Antibody
SKU:
CAB15298
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-449 of human PCOLCE (NP_002584.2).
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.
Purification Method:
Affinity purification
Gene ID:
5118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using PCOLCE Rabbit pAb (CAB15298) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
