PCNA Rabbit Monoclonal Antibody (CAB12427)
- SKU:
- CAB12427
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PCNA Rabbit Monoclonal Antibody |
SKU: | CAB12427 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,African green monkey |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 162-261 of human PCNA (NP_002583.1). |
Sequence: | CAKD GVKF SASG ELGN GNIK LSQT SNVD KEEE AVTI EMNE PVQL TFAL RYLN FFTK ATPL SSTV TLSM SADV PLVV EYKI ADMG HLKY YLAP KIED EEGS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:2000 - 1:10000 |
Synonyms: | ATLD2; PCNA |
Positive Sample: | HeLa cells,MCF7 cells,293T cells,C2C12 cells,COS-7 cells,Mouse spleen,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus |
Calculated MW: | 29kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Purification Method: | Affinity purification |
Gene ID: | 5111 |
Clone Number: | ARC51324 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |