The PCNA Polyclonal Antibody (PACO51078) is a highly specific research tool designed for the detection of Proliferating Cell Nuclear Antigen (PCNA) in various biological samples. PCNA is an essential protein involved in DNA replication and repair, making it a crucial marker for studying cell proliferation and DNA synthesis.Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the PCNA protein, researchers can accurately detect and analyze its expression levels in different cell types, offering valuable insights into cellular processes such as cell division and DNA damage repair mechanisms.
Given the importance of PCNA in maintaining genomic stability and regulating cell proliferation, this antibody is ideal for studies in cancer research, cell biology, and genetics. Its ability to accurately detect PCNA expression provides researchers with a powerful tool for investigating the roles of this protein in various physiological and pathological conditions, ultimately aiding in the development of novel therapeutic strategies targeting cell growth and DNA repair pathways.
Antibody Name:
PCNA Antibody (PACO51078)
Antibody SKU:
PACO51078
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Arabidopsis thaliana
Immunogen:
Recombinant Arabidopsis thaliana Proliferating cellular nuclear antigen 1 protein (1-263AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: PCNA antibody at 2.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 59 kDa. Observed band size: 59 kDa..
Background:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
UniProt Protein Details:
NCBI Summary:
Encodes putative proliferating cell nuclear antigen involved in cell cycle regulation. May be sumoylated.
