PCMT1 Rabbit Polyclonal Antibody (CAB6684)
- SKU:
- CAB6684
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PCMT1 Rabbit Polyclonal Antibody |
SKU: | CAB6684 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-286 of human PCMT1 (NP_001238978.1). |
Sequence: | KSGG ASHS ELIH NLRK NGII KTDK VFEV MLAT DRSH YAKC NPYM DSPQ SIGF QATI SAPH MHAY ALEL LFDQ LHEG AKAL DVGS GSGI LTAC FARM VGCT GKVI GIDH IKEL VDDS VNNV RKDD PTLL SSGR VQLV VGDG RMGY AEEA PYDA IHVG AAAP VVPQ ALID QLKP GGRL ILPV GPAG GNQM LEQY DKLQ DGSI KMKP LMGV IYVP LTDK EKQW SRDE L |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | PIMT; PCMT1 |
Positive Sample: | MCF7,HepG2,293T,A-431,Mouse liver,Mouse brain,Rat brain,Rat heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5110 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |