PCK1 Monoclonal Antibody (CAB22172)
- SKU:
- CAB22172
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | PCK1 Monoclonal Antibody |
SKU: | CAB22172 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 523-622 of human PCK1 (NP_002582.3). |
Sequence: | GKFL WPGF GENS RVLE WMFN RIDG KAST KLTP IGYI PKED ALNL KGLG HINM MELF SISK EFWE KEVE DIEK YLED QVNA DLPC EIER EILA LKQR ISQM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | PCKDC; PEPCK1; PEPCKC; PEPCK-C; PCK1 |
Positive Sample: | Hep G2,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 69kDa |
Observed MW: | 69kDa |
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Purification Method: | Affinity purification |
Gene ID: | 5105 |
Clone Number: | ARC56074 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |