The PCIF1 Polyclonal Antibody is a valuable tool for researchers studying the protein PCIF1, which is involved in RNA splicing and regulates gene expression. This antibody, generated in-house using rabbits, exhibits high specificity for human samples and is suitable for use in Western blot applications. By binding to the PCIF1 protein, this antibody enables the detection and analysis of PCIF1 in various cell types, making it an essential reagent for researchers in the fields of RNA biology, gene regulation, and cancer research.PCIF1 is a key player in the RNA splicing process, where it modulates the splicing efficiency of specific genes.
Dysregulation of PCIF1 expression has been linked to various diseases, including cancer, neurodevelopmental disorders, and genetic syndromes. Investigating the function of PCIF1 is crucial for understanding its role in disease pathogenesis and potentially identifying novel therapeutic targets. Researchers can rely on the PCIF1 Polyclonal Antibody for accurate and reliable detection of PCIF1 in their experimental studies, advancing our knowledge of this important protein and its implications in human health.
Product Name:
PCIF1 Polyclonal Antibody
SKU:
CAB21596
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PCIF1 (NP_071387.1).
Enables RNA polymerase II C-terminal domain phosphoserine binding activity; S-adenosyl-L-methionine binding activity; and mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA methylation; negative regulation of translation; and positive regulation of translation. Located in intercellular bridge; microtubule cytoskeleton; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
63935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PCIF1 Rabbit pAb (CAB21596) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.