The PCGF1 Polyclonal Antibody (CAB6338) is a valuable tool for research involving PCGF1, a key regulator of gene expression and cell growth. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the PCGF1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cancer biology and developmental biology.PCGF1 is a member of the polycomb group (PcG) protein family, which plays a crucial role in epigenetic regulation of gene expression.
Dysregulation of PCGF1 has been implicated in various diseases, including cancer and developmental disorders. Understanding the function of PCGF1 is essential for unraveling its role in these pathologies and identifying potential therapeutic targets.Overall, the PCGF1 Polyclonal Antibody offers researchers a reliable tool for investigating the molecular mechanisms underlying PCGF1 function and its implications in disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of gene regulation and cell growth control.
Product Name:
PCGF1 Rabbit Polyclonal Antibody
SKU:
CAB6338
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-259 of human PCGF1 (NP_116062.2).
PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).
Purification Method:
Affinity purification
Gene ID:
84759
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PCGF1 antibody (CAB6338) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
