The PCF11 Polyclonal Antibody (CAB16533) is a valuable tool for researchers studying PCF11, a protein involved in various cellular processes, including RNA processing and transcriptional regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.PCF11 is known to play a crucial role in regulating gene expression and RNA splicing, making it a key player in maintaining cellular homeostasis. Its dysregulation has been linked to diseases such as cancer, neurological disorders, and developmental abnormalities, making it an attractive target for therapeutic interventions.
By binding specifically to the PCF11 protein, this antibody allows for accurate detection and analysis in a variety of cell types, enabling researchers to further investigate the function and regulation of PCF11. Its application in immunology and oncology research makes it an essential tool for understanding the molecular mechanisms underlying disease pathology and identifying potential therapeutic targets.
Product Name:
PCF11 Rabbit Polyclonal Antibody
SKU:
CAB16533
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1256-1555 of human PCF11 (NP_056969.2).
The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.
Purification Method:
Affinity purification
Gene ID:
51585
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PCF11 Rabbit pAb (CAB16533) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
