PCDHB4 Rabbit Polyclonal Antibody (CAB17733)
- SKU:
- CAB17733
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PCDHB4 Rabbit Polyclonal Antibody |
SKU: | CAB17733 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human PCDHB4 (NP_061761.1). |
Sequence: | EPIR YSVL EETE SGSF VAHL AKDL GLGI GELA SRSA RVLS DDDK QRLQ LDRQ TGDL LLRE KLDR EELC GPIE PCVL HFQV FLEM PVQF FQGE LLIQ DIND HSPI FPER EVLL KILE NSQP GTLF PLLI AEDL DVGS NGLQ KYTI SPNS HFHI LTRN HSEG KKYP DLVQ DKPL DREE QPEF SLTL VALD GGSP PRSG TVMV RILI MDIN DNAP EFVH TPYG VQVL ENSP LDSP IVRV LARD IDAG NFGS VSYG LFQA SDEI KQTF SINE VTGE I |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PCDH-BETA4; PCDHB4 |
Positive Sample: | 293T,Raji,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | plasma membrane, synapse |
Calculated MW: | 87kDa |
Observed MW: | 87kDa |
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Purification Method: | Affinity purification |
Gene ID: | 56131 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |