The PCDH9 Polyclonal Antibody (CAB14760) is a valuable tool for researchers studying PCDH9, a cell adhesion molecule involved in neural development and synapse formation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.PCDH9 plays a crucial role in neuronal connectivity and communication, making it a key player in the development and function of the nervous system. Its involvement in synaptic plasticity and neuronal circuitry highlights its importance in understanding neurological disorders and brain development.
By targeting the PCDH9 protein, this antibody enables researchers to detect and analyze PCDH9 expression in various cell types and tissues, offering insights into its function and potential implications in conditions such as autism, schizophrenia, and other neurodevelopmental disorders. Its versatility and reliability make it an essential tool for studies in neuroscience and neurobiology.
Product Name:
PCDH9 Rabbit Polyclonal Antibody
SKU:
CAB14760
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-600 of human PCDH9 (NP_982354.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
136kDa
Observed MW:
180kDa
This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PCDH9 Rabbit pAb (CAB14760) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
