PCDH8 Rabbit Polyclonal Antibody (CAB14250)
- SKU:
- CAB14250
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PCDH8 Rabbit Polyclonal Antibody |
SKU: | CAB14250 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-750 of human PCDH8 (NP_002581.2). |
Sequence: | VTAA SLDR ERIA EYNL TLVA EDRG APPL RTVR PYTV RVGD ENDN APLF TRPV YEVS VREN NPPG AYLA TVAA RDRD LGRN GQVT YRLL EAEV GRAG GAVS TYVS VDPA TGAI YALR SFDY ETLR QLDV RIQA SDGG SPQL SSSA LVQV RVLD QNDH APVL VHPA PANG SLEV AVPG RTAK DTVV ARVQ ARDA DEGA NGEL AFEL QQQE PREA FAIG RRTG EILL TGDL SQEP PGRV FRAL LVIS DGGR PPLT TTAT VSFV VTAG GGRG PAAP ASAG SPER SRPP GSRL GVSG SVLQ WDTP L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAPC; ARCADLIN; PCDH8 |
Positive Sample: | U-251MG,SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, dendrite, postsynaptic cell membrane, presynaptic cell membrane, synapse. |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
Purification Method: | Affinity purification |
Gene ID: | 5100 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |