The PCDH11X Polyclonal Antibody (PACO11093) is a valuable tool for researchers studying the PCDH11X protein, a member of the protocadherin family involved in cell-cell adhesion and neuronal development. This antibody, generated in rabbits, has high specificity for detecting PCDH11X in human samples and is validated for use in Western blot applications.PCDH11X is known to play a role in brain development and function, making it a key target for studies related to neurobiology, neurodevelopmental disorders, and cognitive functions. The ability of this antibody to detect PCDH11X in various cell types allows for a wide range of experimental applications in neuroscience research.
By using the PCDH11X Polyclonal Antibody, researchers can deepen their understanding of the function and regulation of the PCDH11X protein, ultimately contributing to the development of new therapeutic strategies for neurological disorders and conditions affecting brain development. This antibody is a valuable tool for unlocking the mysteries of the brain and advancing our knowledge of neurobiology.
PCDH11X: Potential calcium-dependent cell-adhesion protein. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq21.3Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion
UniProt Protein Details:
NCBI Summary:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
