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PCCB Polyclonal Antibody (CAB23599)

SKU:
CAB23599
€129
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Description

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Product Name:PCCB Polyclonal Antibody
SKU:CAB23599
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 260-539 of human PCCB (NP_000523.2).
Sequence:AFEN DVDA LCNL RDFF NYLP LSSQ DPAP VREC HDPS DRLV PELD TIVP LEST KAYN MVDI IHSV VDER EFFE IMPN YAKN IIVG FARM NGRT VGIV GNQP KVAS GCLD INSS VKGA RFVR FCDA FNIP LITF VDVP GFLP GTAQ EYGG IIRH GAKL LYAF AEAT VPKV TVIT RKAY GGAY DVMS SKHL CGDT NYAW PTAE IAVM GAKG AVEI IFKG HENV EAAQ AEYI EKFA NPFP AAVR GFVD DIIQ PSST RARI CCDL DVLA SKKV QRPW RKHA NIPL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:PCCB
Positive Sample:HepG2,Mouse kidney
Conjugate:Unconjugated
Cellular Localization:Mitochondrion matrix.
Calculated MW:58kDa
Observed MW:60kDa

The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:5096
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using PCCB Rabbit pAb (CAB23599) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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