PCCA Rabbit Polyclonal Antibody (CAB9486)
- SKU:
- CAB9486
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PCCA Rabbit Polyclonal Antibody |
SKU: | CAB9486 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA (NP_000273.2). |
Sequence: | ISKL ITYG SDRT EALK RMAD ALDN YVIR GVTH NIAL LREV IINS RFVK GDIS TKFL SDVY PDGF KGHM LTKS EKNQ LLAI ASSL FVAF QLRA QHFQ ENSR MPVI KPDI ANWE LSVK LHDK VHTV VASN NGSV FSVE VDGS KLNV TSTW NLAS PLLS VSVD GTQR TVQC LSRE AGGN MSIQ FLGT VYKV NILT RLAA ELNK FMLE KVTE DTSS VLRS PMPG VVVA VSVK PGDA VAEG QEIC VIEA MKMQ NSMT AGKT GTVK SVHC QAGD TVGE GDLL VELE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 IHC-P,1:50 - 1:200 |
Synonyms: | PCCA |
Positive Sample: | Mouse pancreas,Mouse liver,Mouse brain,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5095 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |