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PCBP1 Monoclonal Antibody [PAT2A10AT] (CPAB0595)

SKU:
CPAB0595
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2A10AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

PCBP1 Monoclonal Antibody [PAT2A10AT] (CPAB0595)

The PCBP1 Polyclonal Antibody (CPAB0595) is a key tool for researchers studying PCBP1, a protein involved in RNA binding and regulation. This antibody, developed from rabbits, shows high reactivity with human samples and is validated for use in various applications including Western blotting. By binding specifically to the PCBP1 protein, this antibody enables the detection and analysis of PCBP1 in different cell types, making it an excellent choice for studies in molecular biology and cancer research.PCBP1, also known as poly(rC)-binding protein 1, is a multifunctional protein involved in various cellular processes such as RNA metabolism, transcriptional regulation, and cell proliferation.

Its dysregulation has been linked to diseases such as cancer and neurological disorders, highlighting the importance of further research into its function and mechanisms of action. By studying PCBP1, researchers can gain valuable insights into disease pathways and potentially identify new therapeutic targets for various conditions.

Product Name:PCBP1 Antibody
Product Sku:CPAB0595
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PCBP1 mAb, clone PAT2A1AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PCBP1 protein 1-163 amino acids purified from Ecoli.
Clone:PAT2A10AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PCBP1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:PCBP1 is a single-stranded nucleic acid binding protein that binds preferentially to oligo dC. PCBP1 plays a role in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. PCBP1 along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. PCBP1 and PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.
Synonyms:Poly(rC) binding protein 1, hnRNP-E1, hnRNP-X, HNRPE1, HNRPX, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, PCBP1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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