The PCB Rabbit Monoclonal Antibody (CAB8980) is a cutting-edge tool for researchers studying PCB, a group of environmental contaminants known to have harmful effects on human health. This antibody, raised in rabbits, is highly specific and sensitive for detecting PCB molecules in various samples, making it ideal for use in a range of research applications.With its high affinity and specificity for PCB, this monoclonal antibody allows for accurate and reliable detection and quantification of PCB levels in environmental samples, biological tissues, and other relevant materials. Its versatility in applications such as ELISA, immunohistochemistry, and flow cytometry makes it a valuable asset for researchers investigating the impact of PCB exposure on human health and the environment.
By utilizing the PCB Rabbit Monoclonal Antibody (CAB8980), researchers can better understand the mechanisms of PCB toxicity, facilitate risk assessment studies, and develop strategies for mitigating the harmful effects of these pervasive environmental pollutants. This antibody is a powerful tool for advancing scientific knowledge and ultimately protecting public health and the environment from the adverse effects of PCB contamination.
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5091
Clone Number:
ARC1371
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Pyruvate carboxylase (PC) Rabbit mAb (CAB8980) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
