PBXIP1 Rabbit Polyclonal Antibody (CAB8790)
- SKU:
- CAB8790
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PBXIP1 Rabbit Polyclonal Antibody |
SKU: | CAB8790 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2). |
Sequence: | MASC PDSD NSWV LAGS ESLP VETL GPAS RMDP ESER ALQA PHSP SKTD GKEL AGTM DGEG TLFQ TESP QSGS ILTE ETEV KGTL EGDV CGVE PPGP GDTV VQGD LQET TVVT GLGP DTQD LEGQ SPPQ SLPS TPKA AWIR EEGR CSSS DDDT DVDM EGLR RRRG REAG PPQP MVPL AVEN QAGG EGAG GE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HPIP; PBXIP1 |
Positive Sample: | HeLa,LO2,BT-474,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytoskeleton. |
Calculated MW: | 81kDa |
Observed MW: | 110kDa |
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.
Purification Method: | Affinity purification |
Gene ID: | 57326 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |